Prenatal Exposure to Valproic Acid Affects Microglia and Synaptic Ultrastructure in a Brain-Region-Specific Manner in Young-Adult Male Rats: Relevance to Autism Spectrum Disorders

Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental conditions categorized as synaptopathies. Environmental risk factors contribute to ASD aetiology. In particular, prenatal exposure to the anti-epileptic drug valproic acid (VPA) may increase the risk of autism. In the pr...

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Udgivet i:Int J Mol Sci
Main Authors: Gąssowska-Dobrowolska, Magdalena, Cieślik, Magdalena, Czapski, Grzegorz Arkadiusz, Jęśko, Henryk, Frontczak-Baniewicz, Małgorzata, Gewartowska, Magdalena, Dominiak, Agnieszka, Polowy, Rafał, Filipkowski, Robert Kuba, Babiec, Lidia, Adamczyk, Agata
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279050/
https://ncbi.nlm.nih.gov/pubmed/32443651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103576
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