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CARs: Beyond T Cells and T Cell-Derived Signaling Domains

When optimizing chimeric antigen receptor (CAR) therapy in terms of efficacy, safety, and broadening its application to new malignancies, there are two main clusters of topics to be addressed: the CAR design and the choice of transfected cells. The former focuses on the CAR construct itself. The uti...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sievers, Nico M., Dörrie, Jan, Schaft, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279007/
https://ncbi.nlm.nih.gov/pubmed/32429316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103525
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