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MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment
Limited knowledge of the mechanisms that govern the self-renewal of human haematopoietic stem cells (HSCs), and why this fails in culture, have impeded the expansion of HSCs for transplantation(1). Here we identify MLLT3 (also known as AF9) as a crucial regulator of HSCs that is highly enriched in h...
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| Опубликовано в: : | Nature |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7278275/ https://ncbi.nlm.nih.gov/pubmed/31776511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1790-2 |
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