Impact of Heat on Coil Hydrodynamic Size Yields the Energetics of Denatured State Conformational Bias

Conformational equilibria in the protein denatured state have key roles regulating folding, stability, and function. The extent of conformational bias in the protein denatured state under folding conditions, however, has thus far proven elusive to quantify, particularly with regard to its sequence d...

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Veröffentlicht in:J Phys Chem B
Hauptverfasser: English, Lance R., Voss, Sarah M., Tilton, Erin C., Paiz, Elisia A., So, Stephen, Parra, George L., Whitten, Steven T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278112/
https://ncbi.nlm.nih.gov/pubmed/31679343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b09088
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