טוען...
Interleukin-6-knockdown of chimeric antigen receptor-modified T cells significantly reduces IL-6 release from monocytes
BACKGROUND: T cells expressing a chimeric antigen receptor (CAR) engineered to target CD19 can treat leukemia effectively but also increase the risk of complications such as cytokine release syndrome (CRS) and CAR T cell related encephalopathy (CRES) driven by interleukin-6 (IL-6). Here, we investig...
שמור ב:
| הוצא לאור ב: | Exp Hematol Oncol |
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| Main Authors: | , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7278071/ https://ncbi.nlm.nih.gov/pubmed/32523801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-020-00166-2 |
| תגים: |
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