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Novel Splice Site Pathogenic Variant of EFTUD2 Is Associated with Mandibulofacial Dysostosis with Microcephaly and Extracranial Symptoms in Korea

Elongation factor Tu guanosine-5’-triphosphate (GTP) binding domain containing 2 (EFTUD2) encodes a major component of the spliceosomal GTPase and, if mutated, causes mandibulofacial dysostosis with microcephaly (MFDM; MIM#610536). Despite the increasing number of potentially pathogenic variants rep...

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Detalles Bibliográficos
Publicado en:Diagnostics (Basel)
Main Authors: Kim, So Young, Lee, Da-hye, Han, Jin Hee, Choi, Byung Yoon
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277841/
https://ncbi.nlm.nih.gov/pubmed/32408545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics10050296
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