Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy

Design and development of potential pyruvate dehydrogenase kinase 3 (PDK3) inhibitors have gained attention because of their possible therapeutic uses in lung cancer therapy. In the present study, the binding affinity of naturally occurring alkaloids, hordenine, vincamine, tryptamine, cinchonine, an...

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Publicat a:Biomedicines
Autors principals: Anwar, Saleha, Mohammad, Taj, Shamsi, Anas, Queen, Aarfa, Parveen, Shahnaz, Luqman, Suaib, Hasan, Gulam Mustafa, Alamry, Khalid A., Azum, Naved, Asiri, Abdullah M., Hassan, Md. Imtaiyaz
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277448/
https://ncbi.nlm.nih.gov/pubmed/32422877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8050119
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