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Metabolic acidosis stimulates the production of the antimicrobial peptide cathelicidin in rabbit urine

Intercalated cells of the collecting duct (CD) are critical for acid-base homeostasis and innate immune defense of the kidney. Little is known about the impact of acidosis on innate immune defense in the distal nephron. Urinary tract infections are mainly due to Escherichia coli and are an important...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Peng, Hu, Purkerson, Jeffrey M., Schwaderer, Andy L., Schwartz, George J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276924/
https://ncbi.nlm.nih.gov/pubmed/28747361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00701.2016
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