Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy

BACKGROUND: Sleep Disordered Breathing (SDB) is associated with a wide range of pathophysiological changes due, in part, to hypoxemia during sleep. We sought to identify gene transcription associations with measures of SDB and hypoxemia during sleep, and study their response to treatment. METHODS: I...

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Vydáno v:EBioMedicine
Hlavní autoři: Sofer, Tamar, Li, Ruitong, Joehanes, Roby, Lin, Honghuang, Gower, Adam C., Wang, Heming, Kurniansyah, Nuzulul, Cade, Brian E., Lee, Jiwon, Williams, Stephanie, Mehra, Reena, Patel, Sanjay R., Quan, Stuart F., Liu, Yongmei, Rotter, Jerome I., Rich, Stephen S., Spira, Avrum, Levy, Daniel, Gharib, Sina A., Redline, Susan, Gottlieb, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276515/
https://ncbi.nlm.nih.gov/pubmed/32512511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102803
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