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Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression
BACKGROUND: Multiple sclerosis (MS) is a chronic immune-mediated disorder of the central nervous system characterized by demyelination, neuroinflammation, and neurodegeneration. Activation of the kynurenine pathway (KP) results from acute and chronic neuroinflammation leading to both immune suppress...
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| Udgivet i: | J Neuroinflammation |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7276083/ https://ncbi.nlm.nih.gov/pubmed/32505212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01844-y |
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