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Incomplete penetrance in primary immunodeficiency: a skeleton in the closet

Primary immunodeficiencies (PIDs) comprise a diverse group of over 400 genetic disorders that result in clinically apparent immune dysfunction. Although classically considered mendelian disorders with complete penetrance, we now understand that absent or partial clinical disease is often noted in in...

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書目詳細資料
發表在:Hum Genet
Main Authors: Gruber, Conor, Bogunovic, Dusan
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275875/
https://ncbi.nlm.nih.gov/pubmed/32067110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-020-02131-9
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