Regulation of phagolysosomal activity by miR-204 critically influences structure and function of retinal pigment epithelium/retina

MicroRNA-204 (miR-204) is expressed in pulmonary, renal, mammary and eye tissue, and its reduction can result in multiple diseases including cancer. We first generated miR-204(−/−) mice to study the impact of miR-204 loss on retinal and retinal pigment epithelium (RPE) structure and function. The RP...

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Udgivet i:Hum Mol Genet
Main Authors: Zhang, Congxiao, Miyagishima, Kiyoharu J, Dong, Lijin, Rising, Aaron, Nimmagadda, Malika, Liang, Genqing, Sharma, Ruchi, Dejene, Roba, Wang, Yuan, Abu-Asab, Mones, Qian, Haohua, Li, Yichao, Kopera, Megan, Maminishkis, Arvydas, Martinez, Jennifer, Miller, Sheldon
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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General Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275778/
https://ncbi.nlm.nih.gov/pubmed/31332443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz171
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