Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma

Glioblastoma multiforme (GBM) is an aggressive cancer without currently effective therapies. Radiation and temozolomide (radio/TMZ) resistance are major contributors to cancer recurrence and failed GBM therapy. Heat shock proteins (HSPs), through regulation of extracellular matrix (ECM) remodeling a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rajesh, Yetirajam, Biswas, Angana, Kumar, Utkarsh, Banerjee, Indranil, Das, Subhayan, Maji, Santanu, Das, Swadesh K., Emdad, Luni, Cavenee, Webster K., Mandal, Mahitosh, Fisher, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275698/
https://ncbi.nlm.nih.gov/pubmed/32409605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921531117
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