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Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells

Alveolar epithelial type II cells (AEC2s) are the facultative progenitors of lung alveoli and serve as the surfactant-producing cells of air-breathing organisms. Although primary human AEC2s are difficult to maintain stably in cell cultures, recent advances have facilitated the derivation of AEC2-li...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Jacob, Anjali, Vedaie, Marall, Roberts, David A., Thomas, Dylan C., Villacorta-Martin, Carlos, Alysandratos, Konstantinos-Dionysios, Hawkins, Finn, Kotton, Darrell N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275645/
https://ncbi.nlm.nih.gov/pubmed/31732721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0220-0
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