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Sex differences in pharmacokinetics predict adverse drug reactions in women

BACKGROUND: Women experience adverse drug reactions, ADRs, nearly twice as often as men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood. Most drugs currently in use were approved based on clinical trials conducted on men, so women may be overmedicated. We d...

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Detalhes bibliográficos
Publicado no:Biol Sex Differ
Main Authors: Zucker, Irving, Prendergast, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275616/
https://ncbi.nlm.nih.gov/pubmed/32503637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-020-00308-5
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