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Charge Reduction of Membrane Proteins in Native Mass Spectrometry Using Alkali Metal Acetate Salts
Native mass spectrometry (MS) provides the capacity to monitor membrane protein complexes and noncovalent binding of ligands and lipids to membrane proteins. The charge states produced by native MS of membrane proteins often result in gas-phase protein unfolding or loss of noncovalent interactions....
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| Pubblicato in: | Anal Chem |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275249/ https://ncbi.nlm.nih.gov/pubmed/32250604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00454 |
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