A negative feedback loop between JNK-associated leucine zipper protein and TGF-β1 regulates kidney fibrosis

Renal fibrosis is controlled by profibrotic and antifibrotic forces. Exploring anti-fibrosis factors and mechanisms is an attractive strategy to prevent organ failure. Here we identified the JNK-associated leucine zipper protein (JLP) as a potential endogenous antifibrotic factor. JLP, predominantly...

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Pubblicato in:Commun Biol
Autori principali: Yan, Qi, Zhu, Kai, Zhang, Lu, Fu, Qiang, Chen, Zhaowei, Liu, Shan, Fu, Dou, Nakazato, Ryota, Yoshioka, Katsuji, Diao, Bo, Ding, Guohua, Li, Xiaogang, Wang, Huiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275040/
https://ncbi.nlm.nih.gov/pubmed/32504044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-1008-z
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