Coagulation factor VIII: Relationship to Cardiovascular Disease Risk and Whole Genome Sequence and Epigenome-Wide Analysis in African Americans

BACKGROUND: Prospective studies have suggested higher factor VIII (FVIII) levels is an independent risk factor for coronary heart disease (CHD) and stroke. However, limited information, including on genetic and epigenetic contributors to FVIII variation, is available specifically among African Ameri...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Raffield, Laura M., Lu, Ake T., Szeto, Mindy D., Little, Amarise, Grinde, Kelsey E., Shaw, Jessica, Auer, Paul L., Cushman, Mary, Horvath, Steve, Irvin, Marguerite R., Lange, Ethan M., Lange, Leslie A., Nickerson, Deborah A., Thornton, Timothy A., Wilson, James G., Wheeler, Marsha M., Zakai, Neil A., Reiner, Alex P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274883/
https://ncbi.nlm.nih.gov/pubmed/31985870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14741
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