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In silico models for evaluating proarrhythmic risk of drugs

Safety evaluation of drugs requires examination of the risk of generating Torsade de Pointes (TdP) because it can lead to sudden cardiac death. Until recently, the QT interval in the electrocardiogram (ECG) has been used in the evaluation of TdP risk because the QT interval is known to be associated...

詳細記述

保存先:
書誌詳細
出版年:APL Bioeng
主要な著者: Hwang, Minki, Lim, Chul-Hyun, Leem, Chae Hun, Shim, Eun Bo
フォーマット: Artigo
言語:Inglês
出版事項: AIP Publishing LLC 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274812/
https://ncbi.nlm.nih.gov/pubmed/32548538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5132618
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