Inhibition of Bruton tyrosine kinase in patients with severe COVID-19

Patients with severe COVID-19 have a hyperinflammatory immune response suggestive of macrophage activation. Bruton tyrosine kinase (BTK) regulates macrophage signaling and activation. Acalabrutinib, a selective BTK inhibitor, was administered off-label to 19 patients hospitalized with severe COVID-1...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Immunol
Main Authors: Roschewski, Mark, Lionakis, Michail S., Sharman, Jeff P., Roswarski, Joseph, Goy, Andre, Monticelli, M. Andrew, Roshon, Michael, Wrzesinski, Stephen H., Desai, Jigar V., Zarakas, Marissa A., Collen, Jacob, Rose, Keith, Hamdy, Ahmed, Izumi, Raquel, Wright, George W., Chung, Kevin K., Baselga, Jose, Staudt, Louis M., Wilson, Wyndham H.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274761/
https://ncbi.nlm.nih.gov/pubmed/32503877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abd0110
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker