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Microbial bile acid metabolites modulate gut RORγ(+) regulatory T cell homeostasis
The metabolic pathways encoded by the human gut microbiome constantly interact with host gene products through numerous bioactive molecules(1). Primary bile acids (BAs) are synthesized within hepatocytes and released into the duodenum to facilitate absorption of lipids or fat-soluble vitamins(2). So...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7274525/ https://ncbi.nlm.nih.gov/pubmed/31875848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1865-0 |
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