Microbial bile acid metabolites modulate gut RORγ(+) regulatory T cell homeostasis

The metabolic pathways encoded by the human gut microbiome constantly interact with host gene products through numerous bioactive molecules(1). Primary bile acids (BAs) are synthesized within hepatocytes and released into the duodenum to facilitate absorption of lipids or fat-soluble vitamins(2). So...

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Publicado en:Nature
Autores principales: Song, Xinyang, Sun, Ximei, Oh, Sungwhan F., Wu, Meng, Zhang, Yanbo, Zheng, Wen, Geva-Zatorsky, Naama, Jupp, Ray, Mathis, Diane, Benoist, Christophe, Kasper, Dennis L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274525/
https://ncbi.nlm.nih.gov/pubmed/31875848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1865-0
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