Origins and characterization of variants shared between databases of somatic and germline human mutations

BACKGROUND: Mutations arise in the human genome in two major settings: the germline and the soma. These settings involve different inheritance patterns, time scales, chromatin structures, and environmental exposures, all of which impact the resulting distribution of substitutions. Nonetheless, many...

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Udgivet i:BMC Bioinformatics
Main Authors: Meyerson, William, Leisman, John, Navarro, Fabio C. P., Gerstein, Mark
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273669/
https://ncbi.nlm.nih.gov/pubmed/32498674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3508-8
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