Iron-Chelating Agent Can Maintain Bone Homeostasis Disrupted by Iron Overload by Upregulating Wnt/Beta-Catenin Signaling

BACKGROUND: The incidence of osteoporotic fractures is increasing. In this study, we explored the activities of Wnt/β-catenin signaling in bone tissues with iron accumulation. METHODS: We established rat bipedal walking models (RBWM), and a portion of our RBWM rats were intraperitoneally injected wi...

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Foilsithe in:Biomed Res Int
Main Authors: Xu, Wei, Yu, Ronghua, Zhu, Xiaodong, Li, Zhikun, Jia, Jianjun, Li, Dachuan, Chen, Yu, Zhang, Xiangyang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi 2020
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273370/
https://ncbi.nlm.nih.gov/pubmed/32596380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8256261
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