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Ghrelin signaling contributes to fasting-induced attenuation of hindbrain neural activation and hypophagic responses to systemic cholecystokinin in rats

In rats, overnight fasting reduces the ability of systemic cholecystokinin-8 (CCK) to suppress food intake and to activate cFos in the caudal nucleus of the solitary tract (cNTS), specifically within glucagon-like peptide-1 (GLP-1) and noradrenergic (NA) neurons of the A2 cell group. Systemic CCK in...

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Pubblicato in:Am J Physiol Regul Integr Comp Physiol
Autori principali: Maniscalco, James W., Edwards, Caitlyn M., Rinaman, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272761/
https://ncbi.nlm.nih.gov/pubmed/32292065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00346.2019
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