cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection

Activation of the inflammasome-caspase-1 axis in lung endothelial cells is emerging as a novel arm of the innate immune response to pneumonia and sepsis caused by Pseudomonas aeruginosa. Increased levels of circulating autacoids are hallmarks of pneumonia and sepsis and induce physiological response...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Renema, Phoibe, Hardy, Kierra S., Housley, Nicole, Dunbar, Grace, Annamdevula, Naga, Britain, Andrea, Spadafora, Domenico, Leavesley, Silas, Rich, Thomas, Audia, Jonathon P., Alvarez, Diego F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272745/
https://ncbi.nlm.nih.gov/pubmed/32186399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00185.2019
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