Human intestinal enteroids as a model of Clostridioides difficile-induced enteritis

Clostridioides difficile is an important nosocomial pathogen that produces toxins to cause life-threatening diarrhea and colitis. Toxins bind to epithelial receptors and promote the collapse of the actin cytoskeleton. C. difficile toxin activity is commonly studied in cancer-derived and immortalized...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Engevik, Melinda A., Danhof, Heather A., Chang-Graham, Alexandra L., Spinler, Jennifer K., Engevik, Kristen A., Herrmann, Beatrice, Endres, Bradley T., Garey, Kevin W., Hyser, Joseph M., Britton, Robert A., Versalovic, James
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272722/
https://ncbi.nlm.nih.gov/pubmed/32223302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00045.2020
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