Antibody responses to the RTS,S/AS01(E) vaccine and Plasmodium falciparum antigens after a booster dose within the phase 3 trial in Mozambique

The RTS,S/AS01(E) vaccine has shown consistent but partial vaccine efficacy in a pediatric phase 3 clinical trial using a 3-dose immunization schedule. A fourth-dose 18 months after the primary vaccination was shown to restore the waning efficacy. However, only total IgG against the immunodominant m...

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Détails bibliographiques
Publié dans:NPJ Vaccines
Auteurs principaux: Sánchez, Lina, Vidal, Marta, Jairoce, Chenjerai, Aguilar, Ruth, Ubillos, Itziar, Cuamba, Inocencia, Nhabomba, Augusto J., Williams, Nana Aba, Díez-Padrisa, Núria, Cavanagh, David, Angov, Evelina, Coppel, Ross L., Gaur, Deepak, Beeson, James G., Dutta, Sheetij, Aide, Pedro, Campo, Joseph J., Moncunill, Gemma, Dobaño, Carlota
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272643/
https://ncbi.nlm.nih.gov/pubmed/32550014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0192-7
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