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Enhancement of gene expression noise from transcription factor binding to genomic decoy sites

The genome contains several high-affinity non-functional binding sites for transcription factors (TFs) creating a hidden and unexplored layer of gene regulation. We investigate the role of such “decoy sites” in controlling noise (random fluctuations) in the level of a TF that is synthesized in stoch...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dey, Supravat, Soltani, Mohammad, Singh, Abhyudai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272470/
https://ncbi.nlm.nih.gov/pubmed/32499583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65750-2
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