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Analysis of human metabolism by reducing the complexity of the genome-scale models using redHUMAN

Altered metabolism is associated with many human diseases. Human genome-scale metabolic models (GEMs) were reconstructed within systems biology to study the biochemistry occurring in human cells. However, the complexity of these networks hinders a consistent and concise physiological representation....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Masid, Maria, Ataman, Meric, Hatzimanikatis, Vassily
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272419/
https://ncbi.nlm.nih.gov/pubmed/32499584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16549-2
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