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Maturation and phenotype of pathophysiological neuronal excitability of human cells in tau-related dementia
Frontotemporal dementia and parkinsonism (FTDP-17) caused by the 10+16 splice-site mutation in the gene encoding microtubule-associated protein tau (MAPT) provides an established platform to model tau-related dementia in vitro. Neurons derived from human induced pluripotent stem cells (iPSCs) have b...
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| Publicado en: | J Cell Sci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7272359/ https://ncbi.nlm.nih.gov/pubmed/32299835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.241687 |
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