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Sirtuin-1 regulates organismal growth by altering feeding behavior and intestinal morphology in planarians

Nutrient availability upon feeding leads to an increase in body size in the planarian Schmidtea mediterranea. However, it remains unclear how food consumption integrates with cell division at the organismal level. Here, we show that the NAD-dependent protein deacetylases sirtuins are evolutionarily...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Ziman, Benjamin, Karabinis, Peter, Barghouth, Paul, Oviedo, Néstor J.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272345/
https://ncbi.nlm.nih.gov/pubmed/32265271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.239467
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