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A pilot study on the effect of isotretinoin on serum etonogestrel concentrations in contraceptive implant users

OBJECTIVE: To explore the pharmacokinetic interaction between isotretinoin, a cytochrome P-450 (CYP) inducer and potent teratogen, and the etonogestrel contraceptive implant. STUDY DESIGN: We enrolled healthy reproductive-age women initiating isotretinoin and using an etonogestrel implant. We compar...

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Detalles Bibliográficos
Publicado en:Contraception
Main Authors: Lazorwitz, Aaron, Seale, Rebecca, Davis, Anne, Guiahi, Maryam
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272275/
https://ncbi.nlm.nih.gov/pubmed/32325076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2020.04.011
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