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Clinical Evidence for the Benefits of Burosumab Therapy for X-Linked Hypophosphatemia (XLH) and Other Conditions in Adults and Children

Burosumab (KRN23) is an FGF23 neutralizing antibody that has been the subject of several recent clinical trials principally focused on the treatment of hypophosphatemic rickets in patients with X-linked hypophosphatemia (XLH). Since the first publications in 2014, these trials have demonstrated effi...

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Publicado en:Front Endocrinol (Lausanne)
Autores principales: Schindeler, Aaron, Biggin, Andrew, Munns, Craig F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271822/
https://ncbi.nlm.nih.gov/pubmed/32547492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00338
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