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D’ domain region Arg782-Cys799 of von Willebrand factor contributes to factor VIII binding

In the complex with von Willebrand factor (VWF) factor VIII (FVIII) is protected from rapid clearance from circulation. Although it has been established that the FVIII binding site resides in the N-terminal D’-D3 domains of VWF, detailed information about the amino acid regions that contribute to FV...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Haematologica
Egile Nagusiak: Przeradzka, Małgorzata A., van Galen, Josse, Ebberink, Eduard H. T. M., Hoogendijk, Arie J., van der Zwaan, Carmen, Mertens, Koen, van den Biggelaar, Maartje, Meijer, Alexander B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ferrata Storti Foundation 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271574/
https://ncbi.nlm.nih.gov/pubmed/31558672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.221994
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