Llwytho...
18β-Glycyrrhetinic acid induces human HaCaT keratinocytes apoptosis through ROS-mediated PI3K-Akt signaling pathway and ameliorates IMQ-induced psoriasis-like skin lesions in mice
BACKGROUND: Psoriasis is a chronic inflammatory skin disease affecting 2–3% of the population worldwide. Hyperproliferative keratinocytes were thought to be an amplifier of inflammatory response, thereby sustaining persistence of psoriasis lesions. Agents with the ability to inhibit keratinocyte pro...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | BMC Pharmacol Toxicol |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7271483/ https://ncbi.nlm.nih.gov/pubmed/32493482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-00419-0 |
| Tagiau: |
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