Synthesis of a novel (89)Zr-labeled HER2 affibody and its application study in tumor PET imaging

BACKGROUND: Human epidermal growth factor receptor-2 (HER2) is an essential biomarker for tumor treatment. Affibody is an ideal vector for preparing HER2 specific probes because of high affinity and rapid clearance from normal tissues, etc. Zirconium-89 is a PET imaging isotope with a long half-life...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Xu, Yuping, Wang, Lizhen, Pan, Donghui, Yan, Junjie, Wang, Xinyu, Yang, Runlin, Li, Mingzhu, Liu, Yu, Yang, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271293/
https://ncbi.nlm.nih.gov/pubmed/32495181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-020-00649-7
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