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Sphingolipid biosynthetic pathway is crucial for growth, biofilm formation and membrane integrity of Scedosporium boydii

AIM: Glycosphingolipids are conserved lipids displaying a variety of functions in fungal cells, such as determination of cell polarity and virulence. They have been considered as potent targets for new antifungal drugs. The present work aimed to test two inhibitors, myriocin and DL-threo-1-Phenyl-2-...

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Détails bibliographiques
Publié dans:Future Med Chem
Auteurs principaux: Rollin-Pinheiro, Rodrigo, Rochetti, Victor Pereira, Xisto, Mariana Ingrid Dutra da Silva, Liporagi-Lopes, Livia Cristina, Bastos, Beatriz, Rella, Antonella, Singh, Ashutosh, Rozental, Sonia, Del Poeta, Maurizio, Barreto-Bergter, Eliana
Format: Artigo
Langue:Inglês
Publié: Newlands Press Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7270895/
https://ncbi.nlm.nih.gov/pubmed/31713454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2019-0186
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