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Binding to heparin triggers deleterious structural and biochemical changes in human low-density lipoprotein, which are amplified in hyperglycemia
Low-density lipoprotein (LDL) binding to arterial proteoglycans initiates LDL retention and modification in the arterial wall, triggering atherosclerosis. The details of this binding, its effectors, and its ramifications are incompletely understood. We combined heparin affinity chromatography with b...
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| Wydane w: | Biochim Biophys Acta Mol Cell Biol Lipids |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269877/ https://ncbi.nlm.nih.gov/pubmed/32289504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2020.158712 |
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