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Prelimbic medial prefrontal cortex disruption during adolescence increases susceptibility to helpless behavior in adult rats

Major depressive disorder (MDD) is a disabling mental disorder worldwide. Several animal models have been used to study the neurobiology of this disorder, including the learned helplessness (LH) paradigm, in which susceptible animals show helpless behavior indicated by fails to escape a controllable...

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Detalhes bibliográficos
Publicado no:Eur Neuropsychopharmacol
Main Authors: Uliana, Daniela L., Gomes, Felipe V., Grace, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269819/
https://ncbi.nlm.nih.gov/pubmed/32402649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2020.04.004
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