In-vivo tracking of adoptively transferred natural killer-cells in rhesus macaques using (89)Zirconium-oxine cell labeling and PET imaging

PURPOSE: Trials of adoptive natural killer (NK)-cell immunotherapy for hematological malignancies have thus far shown only marginal effects, despite the potent in-vitro anti-tumor activity of these cells. Homing of infused cells to tumor microenvironments is critical for efficacy but has not been we...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Sato, Noriko, Stringaris, Kate, Davidson-Moncada, Jan K., Reger, Robert N., Adler, Stephen S., Dunbar, Cynthia E., Choyke, Peter L., Childs, Richard W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269806/
https://ncbi.nlm.nih.gov/pubmed/32034075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-2897
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