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Flux, toxicity, and expression costs generate complex genetic interactions in a metabolic pathway

Our ability to predict the impact of mutations on traits relevant for disease and evolution remains severely limited by the dependence of their effects on the genetic background and environment. Even when molecular interactions between genes are known, it is unclear how these translate to organism-l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Adv
Egile Nagusiak: Kemble, Harry, Eisenhauer, Catherine, Couce, Alejandro, Chapron, Audrey, Magnan, Mélanie, Gautier, Gregory, Le Nagard, Hervé, Nghe, Philippe, Tenaillon, Olivier
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Association for the Advancement of Science 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269641/
https://ncbi.nlm.nih.gov/pubmed/32537514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb2236
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