CD8(+) T cells target cerebrovasculature in children with cerebral malaria

BACKGROUND: Cerebral malaria (CM) accounts for nearly 400,000 deaths annually in African children. Current dogma suggests that CM results from infected RBC (iRBC) sequestration in the brain microvasculature and resulting sequelae. Therapies targeting these events have been unsuccessful; findings in...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Riggle, Brittany A., Manglani, Monica, Maric, Dragan, Johnson, Kory R., Lee, Myoung-Hwa, Neto, Osorio Lopes Abath, Taylor, Terrie E., Seydel, Karl B., Nath, Avindra, Miller, Louis H., McGavern, Dorian B., Pierce, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269583/
https://ncbi.nlm.nih.gov/pubmed/31821175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133474
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