Reconciling the Potentially Irreconcilable? Genotypic and Phenotypic Amoxicillin-Clavulanate Resistance in Escherichia coli

Resistance to amoxicillin-clavulanate, a widely used beta-lactam/beta-lactamase inhibitor combination antibiotic, is rising globally, and yet susceptibility testing remains challenging. To test whether whole-genome sequencing (WGS) could provide a more reliable assessment of susceptibility than trad...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Davies, Timothy J., Stoesser, Nicole, Sheppard, Anna E., Abuoun, Manal, Fowler, Philip, Swann, Jeremy, Quan, T. Phuong, Griffiths, David, Vaughan, Alison, Morgan, Marcus, Phan, Hang T. T., Jeffery, Katie J., Andersson, Monique, Ellington, Matt J., Ekelund, Oskar, Woodford, Neil, Mathers, Amy J., Bonomo, Robert A., Crook, Derrick W., Peto, Tim E. A., Anjum, Muna F., Walker, A. Sarah
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269502/
https://ncbi.nlm.nih.gov/pubmed/32205351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02026-19
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