Significant Efficacy of a Single Low Dose of Primaquine Compared to Stand-Alone Artemisinin Combination Therapy in Reducing Gametocyte Carriage in Cambodian Patients with Uncomplicated Multidrug-Resistant Plasmodium falciparum Malaria

Since 2012, a single low dose of primaquine (SLDPQ; 0.25 mg/kg of body weight) with artemisinin-based combination therapies has been recommended as the first-line treatment of acute uncomplicated Plasmodium falciparum malaria to interrupt its transmission, especially in low-transmission settings of...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Vantaux, Amélie, Kim, Saorin, Piv, Eakpor, Chy, Sophy, Berne, Laura, Khim, Nimol, Lek, Dysoley, Siv, Sovannaroth, Mukaka, Mavuto, Taylor, Walter R., Ménard, Didier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Epidemiology and Surveillance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269483/
https://ncbi.nlm.nih.gov/pubmed/32179526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02108-19
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