A Histone Methyltransferase Inhibitor Can Reverse Epigenetically Acquired Drug Resistance in the Malaria Parasite Plasmodium falciparum

Malaria parasites invade and replicate within red blood cells (RBCs), extensively modifying their structure and gaining access to the extracellular environment by placing the plasmodial surface anion channel (PSAC) into the RBC membrane. Expression of members of the cytoadherence linked antigen gene...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Chan, Amanda, Dziedziech, Alexis, Kirkman, Laura A., Deitsch, Kirk W., Ankarklev, Johan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269470/
https://ncbi.nlm.nih.gov/pubmed/32179524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02021-19
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