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A Histone Methyltransferase Inhibitor Can Reverse Epigenetically Acquired Drug Resistance in the Malaria Parasite Plasmodium falciparum

Malaria parasites invade and replicate within red blood cells (RBCs), extensively modifying their structure and gaining access to the extracellular environment by placing the plasmodial surface anion channel (PSAC) into the RBC membrane. Expression of members of the cytoadherence linked antigen gene...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chan, Amanda, Dziedziech, Alexis, Kirkman, Laura A., Deitsch, Kirk W., Ankarklev, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269470/
https://ncbi.nlm.nih.gov/pubmed/32179524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02021-19
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