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Ubqln4 Facilitates Endoplasmic Reticulum-to-Cytosol Escape of a Nonenveloped Virus during Infection

The nonenveloped polyomavirus simian virus 40 (SV40) must penetrate the host endoplasmic reticulum (ER) membrane to enter the cytosol in order to promote infection. How this is accomplished is not entirely clear. Here, we demonstrate that the cytosolic chaperone Ubiquilin4 (Ubqln4) binds directly to...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Liu, Xiaofang, Tsai, Billy
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269444/
https://ncbi.nlm.nih.gov/pubmed/32161173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00103-20
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