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Precursor peptide-targeted mining of more than one hundred thousand genomes expands the lanthipeptide natural product family

BACKGROUND: Lanthipeptides belong to the ribosomally synthesized and post-translationally modified peptide group of natural products and have a variety of biological activities ranging from antibiotics to antinociceptives. These peptides are cyclized through thioether crosslinks and can bear other s...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Walker, Mark C., Eslami, Sara M., Hetrick, Kenton J., Ackenhusen, Sarah E., Mitchell, Douglas A., van der Donk, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268733/
https://ncbi.nlm.nih.gov/pubmed/32493223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06785-7
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