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An empirical Bayes approach to normalization and differential abundance testing for microbiome data

BACKGROUND: Advances in DNA sequencing have offered researchers an unprecedented opportunity to better study the variety of species living in and on the human body. However, the analysis of microbiome data is complicated by several challenges. First, the sequencing depth may vary by orders of magnit...

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Bibliografski detalji
Izdano u:BMC Bioinformatics
Glavni autori: Liu, Tiantian, Zhao, Hongyu, Wang, Tao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268703/
https://ncbi.nlm.nih.gov/pubmed/32493208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03552-z
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