Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

BACKGROUND: Pediatric diffuse intrinsic pontine glioma (DIPG) represents one of the most devastating and lethal brain tumors in children with a median survival of 12 months. The high mortality rate can be explained by the ineligibility of patients to surgical resection due to the diffuse growth patt...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Deligne, Clémence, Hachani, Johan, Duban-Deweer, Sophie, Meignan, Samuel, Leblond, Pierre, Carcaboso, Angel M., Sano, Yasuteru, Shimizu, Fumitaka, Kanda, Takashi, Gosselet, Fabien, Dehouck, Marie-Pierre, Mysiorek, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268424/
https://ncbi.nlm.nih.gov/pubmed/32487241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-020-00198-0
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