Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts

BACKGROUND: Previous studies indicate that soyasaponins may reduce inflammation via modulating toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88) signaling. However, its underlying mechanisms are still not fully understood. METHODS: Lipopolysaccharide (LPS)-challenged inflamed mal...

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Detalhes bibliográficos
Publicado no:BMC Complement Med Ther
Main Authors: Chen, Junbin, Ullah, Hidayat, Zheng, Zhongdaixi, Gu, Xiangfu, Su, Chuhong, Xiao, Lingyu, Wu, Xinglong, Xiong, Fei, Li, Qing, Zha, Longying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268359/
https://ncbi.nlm.nih.gov/pubmed/32493316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-020-2864-2
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